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The proposed targets and effects of TZDs in PT and TAL.
| Nephron segment | Targets | Species | Materials | Effects | Citation |
|---|---|---|---|---|---|
| PT | NBCe1 | Rat Rabbit Human |
Isolated proximal tubule | Stimulation of transport | [12] |
| PT | NHE3 | Rabbit | Isolated proximal tubule | Stimulation of activity | [12] |
| PT | NHE3 | Sprague-Dawley rat | Total kidney homogenate | Enhancement of protein expression | [13] |
| TAL | NKCC2 | Sprague-Dawley rat | Total kidney homogenate | Enhancement of protein expression | [13] |
