Table 1.
Breakdown of 685 differentially methylated Tier 3 CpGs1.
| A: methylation status of 685 CpGs | |
| Hypermethylated | 175 (26%) |
| Hypomethylated | 510 (74%) |
| B: 685-CpG distribution in promoter versus nonpromoter | |
| Promoter | 190 (28%) |
| Nonpromoter | 495 (72%) |
| C: methylation status of 190 promoter CpGs | |
| Hypermethylated | 62 (33%) |
| Hypomethylated | 128 (67%) |
| D: 190-CpG distribution in promoter regions | |
| TSS200 | 29% |
| TSS1500 | 26% |
| 5′UTR | 41% |
| First exon | 4% |
| E: methylation status of 152 genes associated with the 190 CpGs | |
| Hypermethylated | 56 (37%) |
| Hypomethylated | 96 (63%) |
1CpG (cytosine-phosphodiester bond-guanine); TSS (transcription start site); UTR (untranslated region).