Table 2.
Study and baseline characteristics for studies meeting inclusion criteria.
| Reference | Country | Intervention | n | Age (mean ± SD) | % male | Surgery | Study length (months) | Included endpoints |
|---|---|---|---|---|---|---|---|---|
| Choi et al., 2014 [21] | Korea | Harmonic scalpel Monopolar electric coagulator and clips |
128 125 |
52.8 ± 10.7 53.9 ± 10.5 |
60.9% 64.8% |
Gastrectomy with D2 lymph node dissection | 16 | (i) Operating time (ii) Intraoperative blood loss (iii) Postoperative lymphatic drainage (iv) Postoperative complication |
|
| ||||||||
| Chen, 2012 [20] | China | Harmonic scalpel (GEN300) Conventional techniques (knot-tying) |
60 60 |
58.9 ± 19.3 | 65.0% | Distal radical resection of gastric carcinoma and lymphadenectomy | 25 | (i) Operation time (ii) Intraoperative blood loss (iii) Drainage volume |
|
| ||||||||
| Cui et al., 2012 [31] | China | Harmonic scalpel (GEN300) Electrosurgery |
31 31 |
56.4 ± 9.9 58.9 ± 9.2 |
67.7% 58.1% |
Gastrectomy with D2 lymph node dissection | 48 | (i) Operation time (ii) Blood loss volume (iii) Postoperative drainage volume of the first 72 hours (iv) Length of postoperative hospital stay (v) Complication rate |
|
| ||||||||
| Inoue et al., 2012 [26] | Japan | Harmonic Focus Electrosurgery and knot-tying |
30 30 |
64 (41–79)∗
67 (45–92)∗ |
70.0% 73.3% |
Gastrectomy with lymph node dissections (∗combined resection performed in 6 patients in each group) | 11 | (i) Operative time (ii) Blood loss (iii) Postoperative drainage volume (iv) Postoperative hospital stay (v) Surgery-related complications (vi) Number of transfused patients |
|
| ||||||||
| Liu et al., 2010 [29] | China | Harmonic scalpel (GEN300) Electrosurgery |
19 21 |
62 64 |
63.2% 57.1% |
Radical distal resection of gastric carcinoma with D2 dissection | 29 | (i) Operation time (ii) Blood loss (iii) Peritoneal drainage volume of the first 3 days |
|
| ||||||||
| Lu et al., 2008 [24] | China | Harmonic scalpel (GEN300) Monopolar electrosurgery |
26 23 |
66∗
62∗ |
61.5% 56.5% |
Distal radical gastrectomy with D2 dissection† | 11 | (i) Length of operating time for lymphadenectomy (ii) Blood loss in lymphadenectomy (iii) Drainage volume |
|
| ||||||||
| Tsimoyiannis et al., 2002 [28] | Greece | Harmonic scalpel Monopolar electrosurgery |
20 20 |
59 ± 10 62 ± 9 |
80% 75% |
Gastrectomy with D2 dissection | 24 | (i) Operative time (ii) Operative blood loss (iii) Postoperative abdominal drainage (iv) Number of patients transfused (v) Postoperative hospital stay (vi) Frequency of major complication |
|
| ||||||||
| Wang et al., 2010 [30] | China | Harmonic scalpel (GEN300) Monopolar electrosurgery |
38 30 |
61.8 ± 21.5 | 60.30% | Laparoscopic radical distal D2 gastrectomy | 23 | (i) Operation time (ii) Intraoperative bleeding volume (iii) Postsurgery 3-day drainage volume |
|
| ||||||||
| Wilhelm et al., 2011 [23] |
Germany | Harmonic Wave Ultrasound Dissector Electrocautery, sutures, and ligatures |
100 101 |
66 ± 12 64 ± 12 |
60% 61.40% |
Left hemicolectomy‡ and gastrectomy with D2 lymphadenectomy | 24 | (i) Duration of operation (ii) Perioperative blood loss (iii) Intraoperative complications (iv) Duration of hospital stay |
|
| ||||||||
| Xu et al., 2010 [32] | China | Harmonic scalpel Electrosurgery and knot-tying |
23 19 |
61 64 |
60.90% 63.20% |
Distal radical gastrectomy with D2 dissection | 18 | (i) Operation time (ii) Intraoperative blood loss (iii) Postoperative drainage volume |
∗Age reported as median (range).
†Reported outcomes that included only lymphadenectomy patients were excluded from the analysis.
‡Reported outcomes that included patients who received hemicolectomy were excluded from the analysis.