Figure 4.

Closure of clean and contaminated wounds. The areas of full-thickness wounds (initially 1 cm in diameter) were measured from the time of wounding until closure. (A) All full-thickness aseptic wounds closed by day 25. Meth., methicillin; Vanc., vancomycin; (B) Full-thickness wounds contaminated with microorganisms increased in size initially, while TP4-treated wounds did not exhibit the initial expansion and closed somewhat faster (day 21) than vancomycin-treated wounds; (C) Photographs of representative wounds. “Fatal” indicates that no mice survived.