Figure 6.

TP4 affects expression profiles of cell proliferation genes in infected wounds of mice. Adult mice were infected with MRSA, and treated with TP4 or antibiotics, while controls were infected but untreated. On the indicated days, total RNA was isolated from the wound and reverse transcribed for use in real-time qPCR analysis of EGF (A); TGF-β (B); and VEGF (C) gene expression. Values with different letters show significant differences (P < 0.05) between time points, as determined by ANOVA.