Figure 4.
The regulations of Dihydroaustrasulfone alcohol on gelatinase activation. VSMCs were seeded on six-well plates (3 × 105 cells/well) and stimulated with PDGF-BB (20 ng/mL) for 24 h. The cells were then treated with various concentrations of DA (1.75, 3.5 and 7 μM). The conditioned medium was collected to examine the activities of MMP-2 and MMP-9 by gelatin zymography. ** p < 0.01 and *** p < 0.001 compared with the control group (PDGF-BB alone). # p < 0.05 and ## p < 0.01 compared with the control group (PDGF-BB alone).