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Exercise tolerance (A) and heart rate (B) in wild type (WT); α2A/α2CARKO mice placebo (KO) or leucine (KOL), and exercise trained (KOT) or exercise trained leucine-suplemented (KOLT). Data are presented as mean ± SE. n = 9–12 per group. * p < 0.05 vs. Pre; ≠ p < 0.05 vs. WT; # p < 0.05 vs. KO; & p < 0.05 vs. KOL; ‡ p < 0.05 vs. KOT; α p < 0.05 vs. other groups.
