Table 3.
Correlation of clinicopathologic parameters with HMGB1, CC3, Ki6 and RAGE expressions
| HMGB1 + (%) | p | CC3 + (%) | p | Ki67 + (%) | p | RAGE+(%) | p | |
|---|---|---|---|---|---|---|---|---|
| Sex | 0.964 | 0.081 | 0.121 | 0.524 | ||||
| Male | 17(43.59) | 14(35.90) | 22(56.41) | 26(66.67) | ||||
| female | 15(44.12) | 6(17.65) | 13(38.24) | 25(73.53) | ||||
| Age | 0.684 | 0.138 | 0.769 | 0.589 | ||||
| ≤70 y | 14(46.67) | 11(36.67) | 15(50) | 22(73.33) | ||||
| >70 y | 18(41.86) | 9(20.93) | 20(46.51) | 29(67.44) | ||||
| TNM stage | 0.496 | 0.007* | 0.321 | 0.03* | ||||
| Stage I | 3(60) | 2(40) | 2(40) | 1(20) | ||||
| Stage II | 14(41.18) | 7(20.59) | 13(38.24) | 22(64.71) | ||||
| Stage III | 12(40) | 7(20.59) | 17(56.67) | 25(83.33) | ||||
| Stage IV | 3(75) | 4(100) | 3(75) | 3(75) | ||||
| Lymphnodes | 0.565 | 0.551 | 0.007* | 0.050* | ||||
| Negative | 15(40.54) | 9(24.32) | 12(32.43) | 22(59.46) | ||||
| Positive | 17(47.22) | 11(30.56) | 23(63.89) | 29(80.56) | ||||
| Metastasis | 0.196 | 0.001* | 0.265 | 0.818 | ||||
| Negative | 29(42.03) | 16(23.19) | 32(46.38) | 48(69.57) | ||||
| Positive | 3(75) | 4(100) | 3(75) | 3(75) |
+High level expression of proteins
*p value ≤0.05. The difference of protein expressions between clinicopathological parameters was statistically significant