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. 2015 May 28;5:10144. doi: 10.1038/srep10144

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Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Schematic diagram of the peptide-encoding process with SERS nano-identifiers (SERS IDs) and electron microscopic images at each step. a) Peptide-encoding process by attaching SERS IDs. b) Field-emission scanning electron microscope (FE-SEM) images of TentaGel (TG) microbeads without encoding (inset: High-magnification image of TG bead surface). c) Transmission electron microscope image of SERS ID, consisted of Ag NPs embedded in silica nanosphere. d) FE-SEM images of TG beads with SERS encoding (inset: High-magnification image of polymer bead surface bearing SERS IDs).