Table 1.
Association of clinical data and apoE genotype between hyperuricemia patients and control group
| Clinicopathological data | Control group (mean ± SD) ( n = 518) | Hyperuricemia patients (mean ± SD) ( n = 474) | p -value/ |
|---|---|---|---|
| Age (yrs.) | 46.60 ± 11.87 | 47.28 ± 13.44 | 0.401 |
| Stature (cm) | 169.94 ± 5.11 | 170.28 ± 5.39 | 0.312 |
| Weight (kg) | 77.38 ± 9.23 | 80.99 ± 14.19* | <0.05 |
| BMI (kg/m2) | 26.79 ± 2.96 | 27.88 ± 4.42* | <0.001 |
| WC (cm) | 93.72 ± 8.62 | 97.51 ± 11.57* | <0.001 |
| Hip circumferences (cm) | 101.69 ± 7.15 | 102.81 ± 10.57* | 0.045 |
| WHR | 0.92 ± 0.05 | 0.95 ± 0.07* | <0.001 |
| SBP (mmHg) | 110.81 ± 16.34 | 118.28 ± 18.21* | <0.001 |
| DBP (mmHg) | 95.81 ± 21.46 | 103.86 ± 23.38* | <0.001 |
| BUN (mg/dl) | 5.23 ± 1.44 | 6.47 ± 3.57* | <0.001 |
| Cr (mg/dl) | 77.44 ± 18.14 | 88.91 ± 35.23* | 0.003 |
| SUA (mmol/L) | 308.51 ± 60.25 | 495.42 ± 83.66* | <0.001 |
| FBS (mmol/L) | 5.18 ± 1.16 | 5.41 ± 1.80* | 0.017 |
| TG (mmol/L) | 2.88 ± 1.76 | 2.75 ± 1.57* | 0.005 |
| TC (mmol/L) | 4.19 ± 1.48 | 4.24 ± 1.41 | 0.594 |
| HDL-C (mmol/L) | 1.20 ± 0.43 | 1.13 ± 0.61* | 0.043 |
| LDL-C (mmol/L) | 2.65 ± 0.88 | 2.74 ± 0.77 | 0.088 |
| Genotype* | N (%) | N (%) | χ2 value |
| E2/2 | 24 (4.6) | 1 (0.2) | 0.000 |
| E2/3 | 61 (11.8) | 44 (9.3) | |
| E2/4 | 3 (0.6) | 11 (2.3) | |
| E3/3 | 353 (68.1) | 359 (75.7) | |
| E3/4 | 15 (2.9) | 44 (9.3) | |
| E4/4 | 62 (12.0) | 15 (3.2) | |
| Allele | 0.000 | ||
| E2 | 112 (10.8) | 57 (6.0) | |
| E3 | 782 (75.7) | 806 (85.0) | |
| E4 | 139 (13.5) | 85 (9.0) |
A t-test and Pearson Chi-square (χ2) test were used to analyze the data. *The mean difference was significant at the 0.05 level. Data are presented as range, mean ± standard deviation, or percentage. BMI, Body Mass Index; WC, Waist Circumference; WHR, Waist Hip Ratio; SUA, Serum Uric Acid; TG, Serum Triglyceride; TC, Serum Total Cholesterol; HDL-C, Serum High Density Lipoprotein; LDL-C, Serum Low Density Lipoprotein; FBS, Fasting Blood Sugar; BUN, Urea Nitrogen; SCR, Serum Creatinine.