Table 1. Patient Details.

Patient	Age (y) CD diagnosed	Age (y) neoplasm diagnosed	Family history of inflammatory bowel disease	Family history of colorectal cancer	Location of CD	Immunomodulator use	No. of neoplasms	Location of neoplasm	Type of neoplasm(s)	Mutant genes detected	TP53	Kras	p16	Tissues examined over time
1	65	73	No	No	Pancolonic and terminal ileum	No	3	Sigmoid Sigmoid Rectum	Moderately differentiated adenocarcinoma High-grade dysplasia Poorly differentiated adenocarcinoma	TP53	Exon 7 c.731G>A G244D Exon 7 c.742C>T R248W Exon 7 c.742C>T R248W	None	None	1996 1998 2000 2001 2003 2004
2	39	39	No	Yes	Ileocolic	No	1	Sigmoid	Moderately differentiated adenocarcinoma	TP53	Exon 6 c.637C>T R213*	None	None	No
3	44	70	No	No	Small bowel and ileocolic	Yes, azathioprine	1	Jejunum	Moderately differentiated colloid adenocarcinoma	Kras p16	None	c.35G>A G12D	c.442C>A A148T	No
4	29	30	Yes	Yes	Ileocolic	No	1	Right colon	Moderately differentiated adenocarcinoma	TP53	Exon 6 c.637C>T R213*	None	None	No
5	37	65	No	No	Pancolonic terminal ileum, jejunum perianal	Yes, azathioprine	1	Perineal wound in fistula tract	Well-differentiated mucinous adenocarcinoma	TP53 Kras p16	Exon 7 c.733G>A G245S	c.37G>A G13D	c.238C>T R80*	2004 2006 2008
6	37	52	Yes	No	Colonic	No	1	Rectal	Moderately differentiated adenocarcinoma	TP53	Exon 8 c.817C>T R273C	None	None	No
7	71	86	No	No	Colonic	No	2	Transverse colon	Adenomas (DALM)	Kras	None	c.35G>A G12D	None	2009 2010
8	10	32	Yes	Yes	Ileocolic	No	1	Ileum	Poorly differentiated mucinous adenocarcinoma	None	None	None	None	No
9	45	46	No	No	Ileocolic perianal	No	1	Right colon	Poorly differentiated adenocarcinoma	None	None	None	None	No
10	78	79	No	No	Ileocolic	No	1	Right colon	Mucinous moderately differentiated adenocarcinoma	None	None	None	None	No

DALM, dysplasia-associated lesion or mass as adenoma was in area of colitis.