Fig. 3.
Androgen-responsive tissue weights in wild-type and knockout mice. Tissues were dissected from male mice of the indicated ages and 5α-reductase genotypes (WT, wild-type; 2KO, type 2 knockout; DKO, type 1 and 2 double knockout) and weighed. Plotted values are expressed as milligrams of tissue per g BW and represent the mean ± SEM of values obtained from 7–12 animals for each time point and genotype. Asterisks above the histogram bars indicate organ weights that were significantly different (P ≤ 0.05) from those of wild-type mice. A, Prostate; B, seminal vesicles plus coagulating glands; C, testes.