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hAbs isolated during acute DENV infection in BLT-NSG mice bind intact virions. Twenty-four hAbs were tested for their ability to bind inactivated DENV-2 lysates (DENV-2 Ag), soluble rE protein, and intact DENV virions. Recognition of DENV determinants by hAbs isolated from splenocytes at (a) d7or (b) d45 post-DENV infection. The majority of hAbs isolated at d7 and d45 recognize DENV-2 inactivated lysates and intact DENV virions. One of two representative experiments is shown
