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. 2015 May 28;16:129. doi: 10.1186/s12891-015-0584-4

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© Kiyama et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Subclass-based ANA test of a patient with Sjögren’s syndrome (SS #4) showing IgG4-type ANA. ANA patterns differed among IgG subclasses. Total IgG showed Speckled, while IgG2 showed Speckled + Cyto, IgG1 and IgG3 showed Nucleolar + Cyto (with atypical cytoplasmic spots), and IgG4 showed Peripheral. Bar = 20 μm. Cyto: cytoplasmic