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. 2015 May 28;8:33. doi: 10.1186/s13039-015-0136-5

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© Stevens-Kroef et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Comparison of karyotyping and microarray-based profiling in two patients with complex karyotypes. Karyotypes and microarray-based genomic profiles from patient 4521 (panel A and B) and 4899 (panel C and D). CNA observed with microarray-based genomic profiling are marked by arrows, including a 12 Mb focal loss of chromosome 4q24q26 (blue arrow).