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. 2015 May 19;34(1):50. doi: 10.1186/s13046-015-0152-7

Table 4.

mem-PankoMabGEX staining is an independent prognosticator for advanced 10-year and overall survival

10-year survival Overall survival
95% CI 95% CI
Covariate Coefficient (b i ) [HR Exp (b i )] Lower Upper P-value Coefficient (b i ) [HR Exp (b i )] Lower Upper P-value
Histology (NST vs. other) −0.49 0.61 0.16 2.38 ns −0.31 0.73 0.23 2.34 ns
Grading (G1. G2 vs. G3) −0.51 0.60 0.18 1.97 ns −0.59 0.55 0.19 1.63 ns
pT (pT1 vs. pT2-pT4) −0.17 0.84 0.30 2.36 ns −0.06 0.94 0.39 2.26 ns
pN (pN0 vs. pN1-pN3) 0.61 1.84 0.63 5.40 ns 1.06 2.89 1.11 7.53 .030
CIS (fraction within the invasive carcinoma) (no vs. yes) 0.08 1.08 0.40 2.97 ns 0.28 1.32 0.57 3.06 ns
ER (neg. vs. pos.) −1.53 0.22 0.05 0.94 .041 −1.66 0.19 0.05 0.80 .023
PR (neg. vs. pos.) 0.10 1.10 0.28 4.28 ns 0.37 1.45 0.43 4.91 ns
Her2 (neg. vs. pos.) 0.92 2.52 0.56 11.35 ns 0.67 1.95 0.46 8.20 ns
age (≤55y vs. > 55 y.) 0.75 2.11 0.71 6.30 ns 0.28 1.32 0.55 3.18 ns
mem-PankoMabGEX™ (neg. vs. pos.) −2.42 0.09 0.01 0.70 .022 −1.21 0.30 0.09 0.96 .042