Table 1.
Significantly enriched KEGG pathways associated with differentially expressed proteins (DEPs) (pregnant vs . non-pregnant) in the endometrial caruncular (C) and intercaruncular (IC) areas
| Comparison | Term | Count | P- value |
|---|---|---|---|
| pregnant vs. non-pregnant (C areas) | Amino sugar and nucleotide sugar metabolism | 5 | 7.30E-04 |
| Glyoxylate and dicarboxylate metabolism | 3 | 5.00E-03 | |
| Aminoacyl-tRNA biosynthesis | 4 | 7.00E-03 | |
| Glycolysis / Gluconeogenesis | 4 | 1.70E-02 | |
| Pentose phosphate pathway | 3 | 2.30E-02 | |
| Galactose metabolism | 3 | 2.30E-02 | |
| Lysosome | 5 | 2.50E-02 | |
| Citrate cycle (TCA cycle) | 3 | 3.70E-02 | |
| Starch and sucrose metabolism | 3 | 4.70E-02 | |
| pregnant vs. non-pregnant (IC areas) | Valine, leucine and isoleucine degradation | 8 | 8.50E-05 |
| Pyruvate metabolism | 7 | 2.50E-04 | |
| Proteasome | 7 | 6.60E-04 | |
| Citrate cycle (TCA cycle) | 6 | 8.60E-04 | |
| Ribosome | 9 | 1.00E-03 | |
| Tryptophan metabolism | 6 | 2.80E-03 | |
| Propanoate metabolism | 5 | 6.70E-03 | |
| Glycolysis / Gluconeogenesis | 6 | 1.10E-02 | |
| Fatty acid metabolism | 5 | 1.40E-02 | |
| Oocyte meiosis | 8 | 1.80E-02 | |
| Glutathione metabolism | 5 | 2.40E-02 | |
| Glyoxylate and dicarboxylate metabolism | 3 | 2.90E-02 | |
| Butanoate metabolism | 4 | 4.30E-02 | |
| Cysteine and methionine metabolism | 4 | 4.30E-02 |
Count: number of proteins associated with the term. P-value: Modified Fisher Exact P-value, EASE Score.