Table 2.
Significantly enriched KEGG pathways associated with differentially expressed proteins (DEPs) (caruncular (C) vs . intercaruncular (IC)) from pregnant and non-pregnant ewes
| Comparison | Term | Count | P- value |
|---|---|---|---|
| C vs. IC areas (pregnant group) | Focal adhesion | 14 | 2.60E-05 |
| ECM-receptor interaction | 8 | 4.40E-04 | |
| Valine, leucine and isoleucine degradation | 5 | 8.70E-03 | |
| Pyruvate metabolism | 4 | 3.10E-02 | |
| Adherens junction | 5 | 3.50E-02 | |
| Amino sugar and nucleotide sugar metabolism | 4 | 4.30E-02 | |
| C vs. IC areas (non-pregnant group) | Ribosome | 8 | 1.40E-03 |
| Antigen processing and presentation | 7 | 2.20E-03 | |
| Spliceosome | 8 | 1.10E-02 | |
| Proteasome | 5 | 1.20E-02 | |
| Pentose and glucuronate interconversions | 3 | 2.70E-02 | |
| Starch and sucrose metabolism | 4 | 3.30E-02 | |
| Phenylalanine metabolism | 3 | 4.50E-02 | |
| Aminoacyl-tRNA biosynthesis | 4 | 4.60E-02 |
Count: number of proteins associated with the term. P-value: Modified Fisher Exact P-value, EASE Score.