. Author manuscript; available in PMC: 2015 May 28.

Published in final edited form as: Genes Immun. 2009 May 21;10(6):596–600. doi: 10.1038/gene.2009.41

Table 1.

Results of the replication study of the most significantly associated SNPs, performed in an HLA-unmatched, independent sample set comprising 554 T1D patients and 841 healthy white blood donors of southern European origin, using pre-designed Taqman SNP Genotyping

SNP	Coordinate	Alleles 1/2	Allele 1 Frequency (%)		p value	OR (95% CI)
SNP	Coordinate	Alleles 1/2	Cases	Controls	p value	OR (95% CI)
rs10946990^*	29504625	C/T	25	26	ns	-
rs2284165^*	30268034	G/C	21	18	ns	-
rs2844650^*	31010512	A/G	7	6	ns	-
rs419434^†	33094727	A/G	18	10	1×10⁻⁸	1.93 (1.52–2.44)
rs2294472	33207188	C/T	45	47	ns	-
rs986522^*	33243940	C/G	54	51	ns	-

Assays (Applied Biosystems, Foster City, CA). Allele frequencies were compared in 2 × 2 contingency tables using Fisher’s exact test with EPI-INFO v.6.0 (Center for Disease Control, Atlanta, GA).

Genotyping was interrupted after analyzing 190 patients vs. 190 controls, because allele frequency did not differ between the two groups.

^†

In complete LD (r²=1) with rs423209.