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Half maximal inhibitory concentration (IC50) and half maximal combination index (CI50) of nanoparticle (NP) formulations in A549 cells
| Formulation | IC50 PTX (μM) | IC50 BCL (μM) | CI50 |
|---|---|---|---|
| PTX NPs | 0.106 | – | – |
| BCL NPs | – | 0.517 | – |
| PTX-BCL NPs (1/5)* | 0.037 | 0.185 | 0.707 |
| PTX-BCL NPs (1/2)* | 0.089 | 0.109 | 1.050 |
Note:
Ratio of PTX/BCL in PTX-BCL NPs
Abbreviations: BCL, baicalein; PTX, paclitaxel.
