. 2015 Mar 5;29(6):2603–2615. doi: 10.1096/fj.14-270348

TABLE 2.

Fasting glucose and insulin concentrations in WT and Ucp1^−/− mice housed at 23°C or 28°C and fed control or methionine-restricted diets for 11 weeks

Characteristic	Housing temperature
	23°C				28°C
	WT		Ucp1^−/−		WT		Ucp1^−/−
	Control	MR	Control	MR	Control	MR	Control	MR
Glucose (mg/dl)	209 ± 14^b	189 ± 7^b^,^c	185 ± 5^b^,^c	160 ± 11^c	177 ± 9^b^,^c	166 ± 14^c	148 ± 5^c	90 ± 10^d
Insulin (ng/ml)	1.3 ± 0.2^b	0.37 ± 0.1^c	0.47 ± 0.1^c	0.26 ± 0.1^c	1.3 ± 0.2^b	0.42 ± 0.1^c	1.4 ± 0.3^b	0.31 ± 0.1^c

Blood glucose was measured after a 6-hour food withdrawal after 10 weeks on diet; serum insulin was measured after 11 weeks on diet after a 4-hour food withdrawal. The serum parameters were compared by a 3-way analysis of variances using genotype, housing temperature, and diet as main effects and testing for interactions. Least squares means were compared using residual variance as the error term and presented as means ± sem (n = 8/group). Means denoted with different superscripts (a–d) differ at P < 0.05.