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Rats were treated with vehicle (Control) or simvastatin at 60 (Sim 60) and 80 mg.kg-1.day-1 (Sim 80) for 14 days. (A) Plasma CK activity. (B) Plasma [total cholesterol]. *—significantly different from Control and Sim 60 groups. Mean ± SEM. n = 8/group. One way ANOVA with Newman-Keul’s post-hoc test. P < 0.05.
