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Predicted targets of the IMD pathway.
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Potential IMD target genes were identified using in silico analysis of 66 A. gambiae miRNAs (accessed from miRBase http://www.mirbase.org/) using RNAhybrid, miRanda, and PITA software. miRNAs predicted by two and three of the programs are highlighted in red and blue, respectively. The software parameters used are detailed in Materials and Methods. A. gambiae immune gene names, accession numbers, and miRbase miRNA names are given in the table.
