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. 2015 May 28;10(5):e0126355. doi: 10.1371/journal.pone.0126355

Fig 4. Bax and Bcl-2 in DEF vs. AI G93A mice.

Fig 4

Bax (A and B), Bcl-2 (C and D) and Bax/Bcl-2 ratio (E and F) protein content (arbitrary units; AU) in spinal cord of 42 G93A mice: 23 adequate vitamin D3 intake (AI; 1 IU D3/g feed; 12 M, 11 F) and 19 deficient vitamin D3 intake (DEF; 0.025 IU D3/g feed; 10 M, 9 F). Bax (A and B): There was no significant difference in Bax protein content between the diets or between the sexes. Bcl-2 (C and D): There was no significant difference in Bcl-2 protein content between the diets. AI males had 14% higher Bcl-2 protein content vs. AI females (P = 0.048). Bax/Bcl-2 ratio (E and F): DEF mice had 23% higher Bax/Bcl-2 protein content vs. AI (P = 0.076). Data presented as means ± SEM.