Table 3. Effects of simvastatin on the production of polysaccharides, proteins and biomass of S. aureus biofilm.
EPSI (μg/mg) | IPS (μg/mg) | Proteins (μg/mg dry weight) | Biomass (mg) | |
---|---|---|---|---|
Simvastatin | 22.7 ± 9.0 * | 78.6 ± 25.4 * | 2.3 ± 0.4 | 0.66 ± 0.12 * |
Control | 40.7 ± 9.6 | 34.1 ± 8.6 | 1.9 ± 0.4 | 0.93 ± 0.13 |
EPSI- insoluble extracellular polysaccharide. IPS- intracellular polysaccharide. The values of polysaccharides and proteins were normalized by dry weight. Significant differences between the treatment and the control group when:
*p < 0.05 (Kruskal-Wallis).