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. 2015 May 28;10(5):e0126488. doi: 10.1371/journal.pone.0126488

Table 4. Sensitive analyses based on various exclusion criteria.

Studies,N RRs,95%CIs P value P value for heterogeneity I2(%)
total 14 1.05(0.96–1.15) 0.291 0.000 82.8
Country
United States 7 1.01(0.87–1.17) 0.898 0.000 84.1
Europe 5 1.13(0.95–1.35) 0.168 0.001 79.7
Asia 2 1.55(0.45–5.39) 0.491 0.012 84.3
Gender
Female 11 1.07(0.98–1.17) 0.143 0.000 83.5
Male 8 1.13(0.98–1.30) 0.167 0.000 86.5
Effect measure
RRs 10 1.02(0.91–1.15) 0.712 0.000 83.9
ORs 3 1.28(0.91–1.81) 0.162 0.087 59.0
HRs 1 0.98(0.93–1.04) 0.479 NA NA
Sample size
Large(cases ≥ 100) 11 1.03(0.95–1.13) 0.451 0.000 84.5
Small(cases <100) 3 1.72(0.67–4.41) 0.263 0.078 60.9
Adjustment for covariates
Yes 8 0.96(0.83–1.10) 0.529 0.000 75.0
No 6 1.16(1.00–1.34) 0.050 0.000 89.4
NOS score
High(≥5) 13 1.02(0.94–1.12) 0.600 0.000 80.8
Low(<5) 1 1.26(1.12–1.42) 0.000 NA NA
Follow-up duration(years)
≥5 8 0.99(0.86–1.15) 0.978 0.000 83.0
<5 3 1.11(0.99–1.25) 0.075 0.000 87.1
NA 2 1.64(0.52–5.16) 0.394 0.030 78.8

HRs, hazard ratios, ORs, odds ratios, RRs, relative risks, CIs, confidence intervals; NA, not available.