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. 2015 May 28;10(5):e0127385. doi: 10.1371/journal.pone.0127385

Table 2. Description of the 221 infective endocarditis diagnosed among the 2008 patients enrolled in the VIRSTA study, 2009–2011.

Characteristics and outcome n (%)
Median age (years) (IQR)
Male gender 144 (65.2%)
Location of IE
 - aortic 39 (17.7%)
 - mitral 61 (27.0%)
 - aortic and mitral 21 (9.5%)
 - right-sided 17 (7.7%)
 - bilateral 20 (9.1%)
 - cardiac device only* 7 (1.8%)
 - undetermined 56 (25.3%)
Classification according to modified Duke criteria
 - surgically definite 24 (10.9%)
 - clinically definite 197 (89.1%)
  - 2 major criteria 139 (62.9%)
  - 1 major criterion, ≥ 3 minor criteria 56 (25.3%)
  - 5 minor criteria 2 (0.1%)
Severe sepsis without septic shock 56 (25.3%)
Septic shock 57 (25.8%)
Stroke 47 (21.2%)
Other embolic event 67 (30.3%)
Staphylococcus aureus meningitis 13 (5.9%)
Brain abscess 8 (3.6%)
Vertebral osteomyelitis 20 (9.0%)
In-hospital death 78 (35.3%)
12 week case-fatality rate 87 (39.4%)

Abbreviations: IQR: interquartile range; IE: infective endocarditis.