Table 2. Description of the 221 infective endocarditis diagnosed among the 2008 patients enrolled in the VIRSTA study, 2009–2011.
| Characteristics and outcome | n (%) |
|---|---|
| Median age (years) (IQR) | |
| Male gender | 144 (65.2%) |
| Location of IE | |
| - aortic | 39 (17.7%) |
| - mitral | 61 (27.0%) |
| - aortic and mitral | 21 (9.5%) |
| - right-sided | 17 (7.7%) |
| - bilateral | 20 (9.1%) |
| - cardiac device only* | 7 (1.8%) |
| - undetermined | 56 (25.3%) |
| Classification according to modified Duke criteria | |
| - surgically definite | 24 (10.9%) |
| - clinically definite | 197 (89.1%) |
| - 2 major criteria | 139 (62.9%) |
| - 1 major criterion, ≥ 3 minor criteria | 56 (25.3%) |
| - 5 minor criteria | 2 (0.1%) |
| Severe sepsis without septic shock | 56 (25.3%) |
| Septic shock | 57 (25.8%) |
| Stroke | 47 (21.2%) |
| Other embolic event | 67 (30.3%) |
| Staphylococcus aureus meningitis | 13 (5.9%) |
| Brain abscess | 8 (3.6%) |
| Vertebral osteomyelitis | 20 (9.0%) |
| In-hospital death | 78 (35.3%) |
| 12 week case-fatality rate | 87 (39.4%) |
Abbreviations: IQR: interquartile range; IE: infective endocarditis.