Table 1B.

Summary of recent studies examining renal outcomes among living kidney donors

Reference	LKD Participants & Data Source	Comparison Data (if any)	Outcome Measures	Findings Within LKD	Comparison of LKD and Non-LKD
Gibney et al, Transplantation 200722	OPTN data living donor registrations and transplant waitlist registrations in 1993–2005	N/A	Transplant waitlist registrations in prior LKD	44% of 102 LKD waitlisted after donation in the period were black	Black LKD comprised 14.3% of 8,889 LKD in the period, and were over-represented among LKD on the waitlist (P<0.001).
Ibrahim et al, N Engl J Med 2009 17	Retrospective cohort study of 3,698 LKD at one U.S. center in 1963–2007	United States Renal Data System, annual ESRD incidence rates	ESRD based on report of the LKD or recipient GFR measured in 255 LKD	ESRD: 180 cases PMPY Measured GFR: > 60 ml/min/1.73 m2 in 85.5% of the subgroup with GFR data	ESRD in LKD did not exceed national ESRD rate for white Americans (268 cases PMPY)
Lentine et al, N Engl J Med 2010 8	Linkage of OPTN data for 4,650 LKD in 1987–2007 with administrative billing claims from a private health insurer (2000–2007 claims) Median time from donation to end of insurance: 7.7 yrs	N/A for renal outcomes	Claims-based diagnoses of CKD Stage-specific coding examined a sub-group of 2307 with insurance benefits after start of stage-specific coding	CKD diagnosis: Overall, 5.2% at 5 yrs. Approximately twice as likely among black (aHR 2.32, P<0.05) or Hispanic (aHR 1.90, P<0.05) compared to white LKD CKD stage 3 or higher in sub-analysis: more likely in black(aHR, 3.60, P = 0.009) or Hispanic (aHR, 4.23, P = 0.006) vs white LKD Dialysis-requiring CKD in sub-analysis: 0.7% (P=0.02 vs white) and 0.5% Hispanic (P=0.10) LKD, vs 0 cases among white LKD	N/A