Table 3.
Treatment Outcome Parameters (N=50)
| Characteristic | Category | No. | % |
|---|---|---|---|
| Response | Complete response | 2 | 4·0 |
| Partial response | 11 | 22·0 | |
| Stable disease1 | 24 | 48·0 | |
| Increase disease | 7 | 14·0 | |
| Indeterminate | 6 | 12·0 | |
| PFS > 6 Months | No | 23 | 46·0 |
| Yes | 27 | 54·0 | |
| EFS > 6 Months | No | 28 | 56·0 |
| Yes | 22 | 44·0 | |
| Cycles of Treatment | 1 | 8 | 16·0 |
| 2 | 6 | 12·0 | |
| 4 | 8 | 16·0 | |
| 5 | 2 | 4·0 | |
| 6 | 7 | 14·0 | |
| 9+ | 19 | 38·0 | |
| Off Study | No1 | 4 | 8·0 |
| Yes | 46 | 92·0 | |
| Why Off Study | On Study/Unspecified | 4 | 8·0 |
| Disease progression | 31 | 62·0 | |
| Refused further treatment | 4 | 8·0 | |
| Toxicity | 11 | 22·0 | |
| Alive | 29 | 58·0 | |
| Dead | From disease | 19 | 38·0 |
| Undetermined | 2 | 4·0 | |
1
Two patients with stable disease are still on study therapy and could respond. However, all of these patients have been on study for at least 6 months.