Table 1.
Components of the ESCRT machinery in C. neoformans var. grubii
| Complex | Protein name | Locus tag | Accession ID | Saccharomyces cerevisiae protein |
|---|---|---|---|---|
| ESCRT-0 | Vps27 | CNAG_02167 | AFR95653.2 | YNR006W |
| Hse1 | CNAG_05882 | AGV14503.1 | YHL002W | |
| ESCRT-I | Vps23 | CNAG_01720 | AFR97923.1 | YCL008C |
| Vps37 | unidentified | YLR119W | ||
| Vps28 | CNAG_00676 | AFR92805 | YPL065W | |
| Mvb12 | unidentified | YGR206W | ||
| ESCRT-II | Vps22 | CNAG_05704 | AFR96022.1 | YPL002C |
| Vps25 | CNAG_04863 | AFR97353.1 | YJR102C | |
| Vps36 | CNAG_00248 | AFR92381.1 | YLR417W | |
| ESCRT-III | Vps2 | CNAG_05478 | AFR98910.2 | YKL002W |
| Vps20 | CNAG_01265 | AFR94877.1 | YMR077C | |
| Vps24 | CNAG_00421 | AFR92554.2 | YKL041W | |
| Snf7 (Vps32) | CNAG_01583 | AFR97788.1 | YLR025W | |
| Vps60 | CNAG_05715 | AFR96033.1 | YDR486C | |
| Did2 (Vps46) | CNAG_00470 | AFR92602.1 | YKR035W-A | |
| Ist1 | CNAG_02535 | AFR95298.1 | YNL265C | |
| ESCRT-DS | Vps4 | CNAG_04510 | AFR97229.1 | YPR173C |
| Bro1 (Vps31) | CNAG_03372 | AFR96592.1 | YPL084W | |
| Doa4 | CNAG_00757 | AFR92887.2 | YDR069C | |
| Vta1 | CNAG_05747 | AGV14481.1 | YLR181C |
The genes for the proteins indicated in bold were characterized in this study.