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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Ann Neurol. 2015 Apr 22;77(6):942–952. doi: 10.1002/ana.24388

Figure 3.

Figure 3

The probability of a clinical diagnosis of AD (green line) with increasing burden of AD pathology and the additive influences of HS (black line) and TDP-43 pathology (red line) was predicted for a female aged 88 years with 16 years of education controlling for Lewy body pathology, macro and microinfarcts. The probability of a clinical diagnosis of AD was about 30 % per one unit of global AD pathology score (AD pathology score range 0-3.2 units). Concurrence of HS further increased the probability of the clinical diagnosis of AD to about 70 %, and the further addition of TDP-43 pathology increased the probability to about 75%.