Table 1.

Baseline values for all parameters within the model. These values were used in all simulations except for during the parameter sensitivity analysis, in which the parameters were varied with respect to the baseline values listed here. The percentage that each parameter was varied during the parameter sensitivity study is listed in the column on the far right.

Parameter	Description	Value	Vary
Nfrag	Number of initial neovessel parent fragments	2114	--
b0	Branching probability	0.1	--
a	Sprout stress magnitude (per single sprout)	3.72 μPa	50%
b	Sprout stress range	250 μm	25%
N	Sprout stress width (cosine exponent)	2	50%
EM	ECM constitutive model: Stiffness of ground matrix (governs compressive response)	34.52 Pa	50%
Efib	ECM constitutive model: Nonlinear fiber stiffness (governs tensile response)	345.2 Pa	50%
Evess	Microvessel constitutive model: Modulus	3.452 kPa	50%
τ	Viscoelastic time constant	1.08 seconds	25%