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(A) Concentration-dependent inhibition of salicylate 1-monooxygenase-catalyzed biotransformation of CL-20 by DPI. (B) Biotransformation of CL-20 by the native (bar 1), deflavo (bar 2), and reconstituted (bar 3) salicylate 1-monooxygenase (3). A 100% CL-20 biotransformation activity was equivalent to 0.256 ± 0.011 nmol min−1 mg of protein−1. Data are mean percentages of CL-20 biotransformation activity ± standard errors (n = 3).
