Table 4.
Diagnostic Categoriesa and Selected Conditions for 161 Nondeath Serious Reports to the Vaccine Adverse Event Reporting System After Measles, Mumps, and Rubella Vaccine in Adults Aged ≥19 Years, 1 January 2003–31 July 2013
| Body System Category | MMR Vaccine Alone, No. (%) | MMR and Other, Vaccines No. (%) | All MMR Vaccines, No. (%) |
|---|---|---|---|
| Total No. of nondeath serious reports | 66 | 95 | 161 |
| Neurological | 15 (22.7) | 16 (16.8) | 31 (19.3) |
| Encephalitis | 3 | 6 | 9 |
| Seizure | 1 | 4 | 5 |
| Multiple sclerosis | 3 | 2 | 5 |
| Other noninfectious | 9 (13.6) | 18 (18.9) | 27 (16.8) |
| Multiple symptoms | 1 | 5 | 6 |
| Thrombocytopenia | 1 | 2 | 3 |
| Syncope | 0 | 2 | 2 |
| Other infectious | 11 (16.7) | 13 (13.7) | 24 (14.9) |
| Febrile illness | 6 | 1 | 7 |
| Meningitis | 2 | 3 | 5 |
| Varicella rash | 0 | 4 | 4 |
| Guillain-Barré syndrome | 3 (4.5) | 14 (14.7) | 17 (10.6) |
| Allergy | 4 (6.0) | 8 (8.4) | 12 (7.5) |
| Anaphylaxis | 7 (10.6) | 4 (4.2) | 11 (6.8) |
| Musculoskeletal | 2 (3.0) | 8 (8.4) | 10 (6.2) |
| Respiratory | 3 (4.5) | 3 (3.2) | 6 (3.7) |
| Psychiatric | 2 (3.0) | 3 (3.2) | 5 (3.1) |
| Cardiac | 2 (3.0) | 3 (3.2) | 5 (3.1) |
| Local reaction | 2 (3.0) | 3 (3.2) | 5 (3.1) |
| Ear, nose, and throat | 4 (6.0) | 0 (0.0) | 4 (2.5) |
| Gastrointestinal | 2 (3.0) | 1 (1.1) | 3 (1.9) |
| Pregnancy complication | 0 (0.0) | 1 (1.1) | 1 (0.6) |
Abbreviation: MMR, measles, mumps, and rubella.
a Diagnostic categories as described in Velozzi, C et al. Adverse events following influenza A (H1N1) 2009 monovalent vaccines reported to the Vaccine Adverse Event Reporting System, United States, 1 October 2009–31 January 2010. Vaccine 2010; 28:7248–55.