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IFN-α + IL-10 is detrimental to SLE but not control EPC differentiation
EPC/CACs from SLE (n = 18) and control (n = 18) subjects were incubated with 1000 U/ml IFN-α, 30 ng/ml IL-10 or both and mature EC differentiation was assessed as in Fig. 1. Results are presented as the mean (s.e.m.) percentage inhibition of EPC differentiation compared with autologous untreated cells. *P < 0.05, **P < 0.01. CAC: circulating angiogenic cell; EC: endothelial cell; EPC: endothelial progenitor cell.
