Table II.
Association between DMPA use and prevalent fibroids in 1696 young African American women 2010–2013.
| DMPA use | Fibroids |
RR (95% CI) |
||
|---|---|---|---|---|
| N | % | Age adjusted | Fully adjusteda | |
| Never (N = 974) | 254 | 26 | Ref. | Ref. |
| Ever (N = 722) | 124 | 17 | 0.63 (0.52, 0.76) | 0.76 (0.62, 0.93) |
| Duration of use (months) | ||||
| ≤9 (N = 208) | 42 | 20 | 0.74 (0.55, 0.98) | 0.90 (0.67, 1.20) |
| 10–24 (N = 206) | 41 | 20 | 0.76 (0.57, 1.01) | 0.91 (0.68, 1.21) |
| 25–48 (N = 139) | 20 | 14 | 0.53 (0.35, 0.80) | 0.64 (0.42, 0.97) |
| >48 (N = 169) | 21 | 12 | 0.43 (0.29, 0.65) | 0.52 (0.35, 0.79) |
| Time since last use (years)b | ||||
| Current user (N = 146) | 22 | 15 | 0.64 (0.43, 0.94) | 0.77 (0.52, 1.15) |
| 1–4 (N = 188) | 26 | 14 | 0.56 (0.39, 0.81) | 0.65 (0.45, 0.94) |
| 5–8 (N = 174) | 25 | 14 | 0.57 (0.39, 0.82) | 0.68 (0.47, 0.99) |
| ≥9 (N = 213) | 50 | 23 | 0.69 (0.53, 0.90) | 0.87 (0.66, 1.14) |
DMPA, depot medroxyprogesterone acetate.
aAdjusted for age (continuous), parity (nulliparous, 1–2 births, 3+ births), menarche (≤10 years, 11 years or older), and education (Bachelor's degree or higher, all other levels of education).
bOne woman missing time since last use.