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. 2015 Mar 3;24(12):3322–3334. doi: 10.1093/hmg/ddv082

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Published by Oxford University Press 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Figure 5. — Loss of RGCs in the peripheral retinas of Tg-MYOC^Y437H/Sod2^+/− mice. (A) RGCs were labeled by anti-NeuN (upper row) and anti-βIII TUB (lower row) antibodies in the whole-mounted retinas of 10-month-old littermates. Representative images from the peripheral retinas are shown. Scale bar, 100 μm. (B) βIII TUB-positive cells in the peripheral retinas of 10- to 12-month-old mice were counted and plotted as the numbers per area. All the values are presented as mean ± SE and analyzed by one-way ANOVA followed by Tukey's multiple comparisons test. **P < 0.01; n shows the number of analyzed mice.