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Whole-body BMD of 1-month-old (A and D), 3-month-old (B and E), and 9-month-old (C and F) males (A–C) and females (D–G). Data are reported as mean ± S.D. (n = 7–10). *, p < 0.05; **, p < 0.01 versus the wild-type (+/+) sample.