Table 1.

Baseline demographics and characteristics of subjects.

Cohort	ADNI			MADRC
Group	All	CN	MCI	All	CN	MCI
n	624	229	395	524	335	189
Age	75.3 ± 6.7†	76.0 ± 5.0	74.8 ± 7.4	72.6 ± 9.7*†	70.1 ± 9.8	76.9 ± 8.0
Sex (% male)	59.8%**†	52.0%	64.3%	35.5%*†	28.7%	47.6%
Education	15.8 ± 3.0	16.0 ± 2.9	15.7 ± 3.1	16.1 ± 2.6	16.3 ± 2.4	15.7 ± 2.9
AMNART IQ	118.2 ± 11.4*	121.1 ± 10.6	116.6 ± 11.5	121.8 ± 8.8*	123.0 ± 7.5	119.5 ± 10.4
MMSE	27.8 ± 1.8*	29.1 ± 1.0	27.0 ± 1.8	28.5 ± 2.0*	29.2 ± 1.0	27.2 ± 2.6
CDR sum of boxes	1.0 ± 1.0*†	0.0 ± 0.1	1.6 ± 0.9	0.8 ± 1.2*†	0.1 ± 0.3	2.0 ± 1.1

ADNI (Alzheimer’s Disease Neuroimaging Initiative), AMNART IQ (American National Adult Reading Test intelligence quotient), CDR (Clinical Dementia Rating), CN (clinically normal), MADRC (Massachusetts Alzheimer’s Disease Research Center), MCI (mild cognitive impairment), MMSE (Mini-Mental State Examination).

All values represent mean ± standard deviation (except n and sex).

^*p<0.001 for CN vs. MCI within cohort.

^**p<0.01 for CN vs. MCI within cohort.

^†p<0.001 between cohorts.