Table 2.

Baseline individual FAQ item and total FAQ score (mean ± standard deviation).

Cohort	ADNI			MADRC
FAQ Items	All	CN	MCI	All	CN	MCI
“Paying bills/balancing checkbook”*	0.35 ± 0.74	0.03 ± 0.24	0.53 ± 0.87	0.16 ± 0.49	0.02 ± 0.15	0.41 ± 0.75
“Assembling tax records”**	0.44 ± 0.82	0.03 ± 0.26	0.68 ± 0.93	0.17 ± 0.55	0.03 ± 0.19	0.48 ± 0.84
“Shopping alone for clothes or groceries”	0.16 ± 0.49	0.00 ± 0.07	0.25 ± 0.59	0.11 ± 0.41	0.01 ± 0.08	0.29 ± 0.64
“Playing a game of skill such as bridge or chess/working on a hobby”	0.17 ± 0.47	0.00 ± 0.07	0.27 ± 0.57	0.10 ± 0.40	0.01 ± 0.10	0.29 ± 0.66
“Heating water and turning off stove”*	0.07 ± 0.32	0.00 ± 0.00	0.10 ± 0.40	0.06 ± 0.27	0.01 ± 0.11	0.15 ± 0.42
“Preparing a balanced meal”	0.16 ± 0.45	0.00 ± 0.07	0.25 ± 0.55	0.06 ± 0.29	0.00 ± 0.06	0.18 ± 0.47
“Keeping track of current events”	0.20 ± 0.53	0.00 ± 0.07	0.32 ± 0.64	0.08 ± 0.32	0.01 ± 0.09	0.22 ± 0.50
“Paying attention and understanding a TV program”*	0.16 ± 0.43	0.00 ± 0.07	0.25 ± 0.52	0.10 ± 0.34	0.02 ± 0.13	0.25 ± 0.51
“Remembering appointments”**	0.52 ± 0.79	0.05 ± 0.27	0.80 ± 0.86	0.26 ± 0.54	0.04 ± 0.21	0.65 ± 0.70
“Driving or traveling out of the neighborhood”	0.25 ± 0.63	0.01 ± 0.09	0.39 ± 0.75	0.17 ± 0.47	0.03 ± 0.18	0.41 ± 0.68
Total FAQ Score	2.48 ± 3.99	0.14 ± 0.60	3.84 ± 4.46	1.22 ± 2.72	0.17 ± 0.67	3.06 ± 3.79

ADNI (Alzheimer’s Disease Neuroimaging Initiative), CN (clinically normal), FAQ (Functional Activities Questionnaire), MADRC (Massachusetts Alzheimer’s Disease Research Center), MCI (mild cognitive impairment).

FAQ item score range: 0–3 (higher scores indicate greater impairment; 0 = normal or never did but could do now; 1 = has difficulty but does by self or never did but would have difficulty now; 2 = requires assistance; 3 = dependent).

All values represent mean ± standard deviation.

^*FAQ items that best predicted progression from CN to MCI.

^**FAQ items in that best discriminated between CN and MCI subjects.