Table 2.
Single-factor analysis of integrin β1, β2, β3 level
| VTE | INF | CAN | IMD | SUR | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|||||||||||||||
| x2 | OR* | 95% CI | x2 | OR* | 95% CI | x2 | OR* | 95% CI | x2 | OR* | 95% CI | x2 | OR* | 95% CI | |
| β1 | 30.44 | 4.88 | 2.69, 8.83 | 21.94 | 2.76 | 1.78, 4.27 | 23.24 | 3.33 | 2.01, 5.50 | 14.92 | 2.91 | 1.67, 5.07 | 1.80 | 1.50 | 0.82, 2.74 |
| β2 | 22.52 | 3.93 | 2.18, 7.09 | 21.15 | 2.64 | 1.73, 4.04 | 4.97 | 1.80 | 1.07, 3.04 | 8.75 | 2.28 | 1.31, 3.98 | 0.03 | 0.98 | 0.52, 1.85 |
| β3 | 22.67 | 7.18 | 2.87, 17.9 | 12.39 | 3.75 | 1.71, 8.22 | 12.48 | 4.25 | 1.79, 10.04 | 7.78 | 3.55 | 1.38, 9.12 | 1.72 | 0.27 | 0.03, 2.19 |
indicates VTE, INF, CAN, IMD, SUR vs. CONTROL.
The integrin level higher than the control upper limit is defined as positive, and lower than the upper limit is defined as the negative. The relationships between integrin β1, β2, β3 positive exposure and the occurrence of VTE, between VTE group, risk factor groups and control group were compared. The OR value in β1 positive population was 4.88 (95% CI: 2.69-8.83) higher than β1 negative population. In risk factor groups, the highest OR value of 3.33 (95% CI: 2.01-5.50) was found in the malignancy group. The OR value in β2 positive population was 3.93 (95% CI: 2.18-7.09) higher than β2 negative population. In risk factor groups, the highest OR value of 2.64 (95% CI: 1.73-4.04) was found in the acute infection group. The OR value of integrin β3 positive population was 7.18 (95% CI: 2.87-17.92) in VTE group.