Table 1.

Clinical characteristics of high grade osteosarcoma patients included in this study

		n	%
Totala		66	100
NRP1 positivea		7	11
NRP1 negativea		58	89
NRP2 positive		7	11
NRP2 negative		59	89
Gender	female	23	35
	male	43	65
Age (years)	< 10	11	17
	10-24	39	59
	> 24	16	24
Tumor type	Osteoblastic	45	68
	Chondroblastic	11	17
	Fibroblastic	6	9
	Telangiectatic	4	6
Anatomical Site	Tibia/fibula/calcaneus	21	32
	Femur	24	36
	Humerus/ulna	6	9
	Jaws/facies/vertebrae column/pelvis	15	23
Chemotherapy response	Responders	29	44
	Non-responders	23	35
	No neoadjuvant chemotherapy	12	18
	Missing information	2	3
Metastasis	No metastasis	43	65
	Total metastasis	23	35
	Metastasis at diagnosis	5	8
	Metastasis after diagnosis	18	27

^aThe total number of patients evaluated for NRP1 staining = 65.