Table 3.
Trial ID | Actual or target dose | Intervention(mg/kg/dose) | Comparator(mg/kg/dose) | ||
Artesunate | Pyronaridine | Artemisinin-derivative | Partner drug | ||
Kayentao 2012 | Actual dose | 2.2 to 4.4 | 6.7 to 13.3 | 1.3 to 4.0 | 8.0 to 24.0 |
Tshefu 2010 | Target dose | 2.4 to 4.6 | 7.2 to 13.8 | NS | NS |
Rueangweerayut 2012 | Actual dose | 2.4 to 4.7 | 7.1 to 14.0 | 2.5 to 5.0 | 6.2 to 12.5 |
Poravuth 2011 | Target dose | 2.4 to 4.6 | 7.2 to 13.8 | — | 10, 5, 5 |
Ringwald 1996 | Target dose | — | 16, 8, 8 | — | 10, 5, 5 |
Ringwald 1998 | Target dose | — | 8, 8, 8, 8 | — | 10, 10, 5 |
NS = Not specified.