Table 4.
Risk of bias for patient reported symptoms
| Trial ID | Monitoring active or passive? | Outcome data reporting | Blinding adequate? | % of participants included in AE reporting | Independent data analysis | ||||
| Days data collected | Days data reported | Patient | Clinician | Data analysis | AS-Pyr | Control | |||
| Tshefu 2010 | Unclear | 0 to 3, 7, 14, 21, 28, 35, 42 | Unclear | Yes | Yes | Unclear | 100% | 100% | No |
| Kayentao 2012 | Unclear | Unclear | Unclear | No | No | Yes | 100% | 100% | No |
| Rueangweerayut 2012 | Unclear | Unclear | Unclear | No | No | Unclear | 100% | 100% | No |
| Poravuth 2011 | Unclear | Unclear | Unclear | Yes | Yes | Yes | 100% | 100% | Yes |
| Ringwald 1996 | Unclear | Unclear | Unclear | No | No | Unclear | Unclear | Unclear | Yes |
| Ringwald 1998 | Unclear | Unclear | Unclear | No | No | Unclear | 100% | 100% | Yes |