Number of participants (studies)	Second-line injectable drug, culture, indirect		Second-line injectable drug, culture, direct		Sensitivity, P value1	Specificity, P value1
	Sensitivity (95% CI)	Specificity (95% CI)	Sensitivity (95% CI)	Specificity (95% CI)
2507 (19 studies )	76.9% (61.1 to 87.6)	99.5% (97.1 to 99.9)	98.0% (39.6 to 100.0)	97.8% (86.4 to 99.7)	0.202	0.003

Indirect comparisons for the purpose of determining pooled accuracy estimates are not to be confused with indirect testing that pertains to the method for testing with MTBDRsl..

¹Likelihood ratio test for evidence of a significant difference between accuracy estimates.