Table 1.

Map of review showing the number of eligible studies, according to reference standard and target condition, which performed indirect testing

Target condition, drug resistance to...	Reference standard
Culture, n/N (%)	Genetic testing, n/N (%)	Genetic and culture testing, n/N (%)	Culture followed by genetic testing of discordant results, n/N (%)
Fluoroquinolones	16/16 (100)†	7/16 (44)	7/16 (44)	3/16 (19)
Ofloxacin	11/16 (69)	0	0	0
Moxifloxacin	4/16 (25)	0	0	0
Levofloxacin	1/16 (6)	0	0	0
Second-line injectable drugs	14/14 (100)†	6/14 (43)	7/14 (50)	3/14 (21)
Amikacin	9/14 (64)	0	0	0
Kanamycin	8/14 (57)	0	0	0
Capreomycin	10/14 (71)	0	0	0
XDR-TB	8/8 (100)	3/8 (38)	2/8 (25)	0

^†A total of 16 and 14 studies were included that evaluated MTBDRsl against a fluoroquinolone and a second-line injectable drug, culture reference standard. These form the denominators to generate percentages of these studies that included a particular additional reference standard.