Table 2.

Map of review showing the number of eligible studies, according to reference standard and target condition, which performed direct testing

Target condition, drug resistance to...	Reference standard
Culture, n/N (%)	Genetic testing, n/N (%)	Genetic and culture testing, n/N (%)	Culture followed by genetic testing of discordant results, n/N (%)
Fluoroquinolones	7/7 (100)†	0	0	2/7 (29)
Ofloxacin	3/7 (43)	0	0	1/7 (14)
Second-line injectable drugs	6/6 (100)†	0	0	2/5 (40)
Amikacin	4/6 (67)	0	0	1/6 (17)
Kanamycin	4/6 (67)	0	0	0
Capreomycin	6/6 (100)	0	0	0
XDR-TB	3/3 (100)	0	0	1/3 (34)

^†A total of six and five studies were included that evaluated MTBDRsl against a fluoroquinolone and a second-line injectable drug, culture reference standard. These form the denominators to generate percentages of these studies that included a particular additional reference standard.