Van't Veen 1998

Methods	Individual randomised controlled trials
Participants	Dx: SD and dandruff (physician dx implied from text) Excluded: pregnant or breastfeeding Male: beta (50%), keto (46%); age: beta (47 ± 16 years), keto (40 ± 17 years); duration: beta (11 months), keto (17 months)
Interventions	Intervention: 0.1% betamethasone lotion applied twice daily (week 1), once daily (week 2), twice weekly (weeks 3 and 4) (n = 34) Control: 2% ketoconazole hydrogel applied twice weekly for 4 weeks (n = 35)
Outcomes	Global evaluation of cure, symptom score for scaling and pruritus
Notes	Country: The Netherlands; multi-centre study Financial support by Glaxo; adverse effect: folliculitis
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"... randomly allocated..."
Allocation concealment (selection bias)	High risk	"... randomly allocated..."
Baseline comparable?	Low risk	Age, sex and severity
Patient blinded?	High risk	Not reported
Provider blinded?	High risk	Not reported
Outcome assessor blinded?	High risk	Not reported
Co-interventions avoided?	Low risk	Not allowed
Compliance acceptable?	Unclear risk	Not reported
Drop-out acceptable?	Low risk	Beta (5/34), keto (3/35)
Selective outcome reporting acceptable?	Low risk	All outcomes reported
ITT?	Unclear risk	Not reported