Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Failure to achieve complete resolution	6	302	Risk Ratio (M-H, Fixed, 95% CI)	1.17 [0.95, 1.44]
1.1 Scalp only	2	118	Risk Ratio (M-H, Fixed, 95% CI)	1.17 [0.97, 1.42]
1.2 Face and scalp	2	113	Risk Ratio (M-H, Fixed, 95% CI)	1.85 [0.90, 3.79]
1.3 Face only	2	71	Risk Ratio (M-H, Fixed, 95% CI)	0.68 [0.32, 1.47]
2 Failure to achieve complete resolution (long term)	2		Risk Ratio (M-H, Random, 95% CI)	Totals not selected
2.1 28% per week	1		Risk Ratio (M-H, Random, 95% CI)	0.0 [0.0, 0.0]
2.2 2% to 7% per week	1		Risk Ratio (M-H, Random, 95% CI)	0.0 [0.0, 0.0]
3 Decrease in erythema score	3	190	Std. Mean Difference (IV, Fixed, 95% CI)	-0.01 [-0.30, 0.28]
3.1 Face only	1	40	Std. Mean Difference (IV, Fixed, 95% CI)	-0.11 [-0.73, 0.51]
3.2 Scalp only	2	150	Std. Mean Difference (IV, Fixed, 95% CI)	0.02 [-0.30, 0.34]
4 Decrease in erythema score (long term)	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
4.1 Scalp only	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
5 Erythema - Failure to achieve complete resolution	2	195	Risk Ratio (M-H, Random, 95% CI)	0.51 [0.19, 1.38]
5.1 Face and scalp	1	53	Risk Ratio (M-H, Random, 95% CI)	0.24 [0.06, 1.03]
5.2 Scalp only	1	142	Risk Ratio (M-H, Random, 95% CI)	0.71 [0.44, 1.14]
6 Decrease in pruritus score	4	259	Std. Mean Difference (IV, Fixed, 95% CI)	0.15 [-0.09, 0.40]
6.1 Face only	1	40	Std. Mean Difference (IV, Fixed, 95% CI)	-0.14 [-0.76, 0.48]
6.2 Scalp only	3	219	Std. Mean Difference (IV, Fixed, 95% CI)	0.20 [-0.06, 0.47]
7 Decrease in pruritus (long term)	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
7.1 Scalp only	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
8 Pruritus - Failure to achieve complete resolution	2	215	Risk Ratio (M-H, Fixed, 95% CI)	0.53 [0.34, 0.84]
8.1 Face and scalp	1	53	Risk Ratio (M-H, Fixed, 95% CI)	0.28 [0.06, 1.20]
8.2 Scalp only	1	162	Risk Ratio (M-H, Fixed, 95% CI)	0.59 [0.37, 0.95]
9 Decrease in scaling score	5	329	Std. Mean Difference (IV, Random, 95% CI)	0.19 [-0.13, 0.51]
9.1 Face only	1	40	Std. Mean Difference (IV, Random, 95% CI)	-0.32 [-0.95, 0.30]
9.2 Scalp only	3	219	Std. Mean Difference (IV, Random, 95% CI)	0.32 [-0.12, 0.77]
9.3 Face and scalp	1	70	Std. Mean Difference (IV, Random, 95% CI)	0.19 [-0.28, 0.66]
10 Decrease in scaling score (long term)	2	112	Std. Mean Difference (IV, Fixed, 95% CI)	0.71 [0.31, 1.11]
10.1 Scalp only	1	49	Std. Mean Difference (IV, Fixed, 95% CI)	1.96 [1.27, 2.65]
10.2 Face and scalp	1	63	Std. Mean Difference (IV, Fixed, 95% CI)	0.08 [-0.42, 0.57]
11 Scaling - Failure to achieve complete resolution	2	215	Risk Ratio (M-H, Fixed, 95% CI)	0.78 [0.54, 1.12]
11.1 Face and scalp	1	53	Risk Ratio (M-H, Fixed, 95% CI)	0.53 [0.21, 1.39]
11.2 Scalp only	1	162	Risk Ratio (M-H, Fixed, 95% CI)	0.84 [0.57, 1.25]
12 Side effects	8	596	Risk Ratio (M-H, Fixed, 95% CI)	0.56 [0.32, 0.96]
12.1 Scalp only	4	381	Risk Ratio (M-H, Fixed, 95% CI)	0.81 [0.34, 1.93]
12.2 Face and scalp	3	175	Risk Ratio (M-H, Fixed, 95% CI)	0.36 [0.17, 0.78]
12.3 Face only	1	40	Risk Ratio (M-H, Fixed, 95% CI)	3.0 [0.13, 69.52]