Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Failure to achieve complete resolution	9	2559	Risk Ratio (M-H, Random, 95% CI)	0.66 [0.56, 0.78]
1.1 Shampoo	3	248	Risk Ratio (M-H, Random, 95% CI)	0.62 [0.39, 0.99]
1.2 Demulcents	5	531	Risk Ratio (M-H, Random, 95% CI)	0.61 [0.50, 0.74]
1.3 Foam	1	847	Risk Ratio (M-H, Random, 95% CI)	0.76 [0.66, 0.87]
1.4 Gel	1	933	Risk Ratio (M-H, Random, 95% CI)	0.82 [0.77, 0.88]
2 Decrease in erythema score	2		Std. Mean Difference (IV, Fixed, 95% CI)	Totals not selected
2.1 Shampoo	1		Std. Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
2.2 Demulcents	1		Std. Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
3 Erythema - Failure to achieve complete resolution	2	259	Risk Ratio (M-H, Random, 95% CI)	0.54 [0.21, 1.43]
3.1 Shampoo	1	200	Risk Ratio (M-H, Random, 95% CI)	0.78 [0.66, 0.92]
3.2 Cream	1	59	Risk Ratio (M-H, Random, 95% CI)	0.32 [0.13, 0.77]
4 Decrease in pruritus score	3	699	Std. Mean Difference (IV, Fixed, 95% CI)	-0.55 [-0.85, -0.26]
4.1 Demulcents	1	40	Std. Mean Difference (IV, Fixed, 95% CI)	-2.06 [-2.84, -1.28]
4.2 Gel	1	459	Std. Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
4.3 Shampoo	1	200	Std. Mean Difference (IV, Fixed, 95% CI)	-0.30 [-0.62, 0.02]
5 Decrease in scaling score	3	304	Std. Mean Difference (IV, Fixed, 95% CI)	-0.65 [-0.91, -0.39]
5.1 Shampoo	2	264	Std. Mean Difference (IV, Fixed, 95% CI)	-0.47 [-0.75, -0.20]
5.2 Demulcent	1	40	Std. Mean Difference (IV, Fixed, 95% CI)	-2.12 [-2.91, -1.33]
6 Decrease in scaling score (long term)	2		Std. Mean Difference (IV, Fixed, 95% CI)	Subtotals only
6.1 Shampoo	2	264	Std. Mean Difference (IV, Fixed, 95% CI)	-0.54 [-0.82, -0.27]
7 Side effects	6	988	Risk Ratio (M-H, Random, 95% CI)	0.97 [0.58, 1.64]
7.1 Shampoo	3	440	Risk Ratio (M-H, Random, 95% CI)	1.27 [0.47, 3.45]
7.2 Demulcents	2	89	Risk Ratio (M-H, Random, 95% CI)	0.69 [0.29, 1.67]
7.3 Gel	1	459	Risk Ratio (M-H, Random, 95% CI)	0.80 [0.53, 1.20]